Excerpt fromThe Lancet Influenzal Pneumonia Article of 1920

The Lancet JournalWe had hoped to provide you with the entire Lancet Journal article here, however, the Lancet still does not allow reprinting of their aritlces…even those printed 83 years ago… so.

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The Lancet Journal

Influenzal Pneumonia and Hydrogen Peroxide Study of 1919

Title and authors
INFLUENZA PNEUMONIA
THE INTRAVENOUS INJECTION OF HYDROGENS .PEROXIDE.Th
BY T. H.OLIVER, M.A., B.CH. C1NTAB.,M.D. VICT.,
RESIDENT MEDICAL OFFICER. THE ROLL INFIRMARY
BLANCHESTER : AND D. V. MURPHY, M.B., CH.B. N.U.I.,
CAPTAINS, R.A.M.C.

Excerpt:

Theory Underlying the Treatment.
There occurred in Busrah in June and July,1919, a severe epidemic of influenza, most marked among Indian troops, and accompanied in many cases by an exceedingly toxaemic and fatal broncho-pneumonia. It is unfortunately impossible to give statistics of the mortality of the epidemic, but its extent may be gauged from the fact that in one large Indian hospital in which the influenza cases were
segregated in special huts the. death-rate was over 80 per cent in the pneumonia cases with toxic symptoms.

So useless were the usual remedies tried in this latter class of case that we felt justified in giving a trial to any method which held out a prospect of success.

Effect on Patients.
The first case was an Indian with broncho-pneumonia of influenzal origin and intensive toxaemic. He had been delirious for two days previously, and was selected as being the worst case in the ward and to all appearances moribund. Two ounces of a ten-volume solution of H202 were diluted with 8 ounces of normal saline, and the solution made slightly alkaline with 5 minims of liquor ammouiae. This produced a faintly effervescing solution.

Encouraged by the apparent success in this case, we tried. the method on 24 others cases of influenzal pneumonia selecting always those whose condition was apparently hopeless. Of the total of 25 cases, 13 recovered and 12 died, a mortality of 48 percent.

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Quite remarkable that an experimental study born of desperationduring an epidemic in which there was an 80 percent mortality rate should accomplish such a great reduction in mortality, even in such a small sampling of the worst cases.


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